Apparently, the latest version of this Hgh Performance Python is super fast compared to other versions.
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Smart comment:
I agree with you that python is perfectly viable for real-life HPC/scientific computing as long as you profile often and make sure the hot spots in your code use high-performance implementations (typically C bindings through some library).
https://www.reddit.com/r/Python/comments/vd1tyd/highperformance_python/